TY - JOUR T1 - The view of the native gauges of blood pressure – focus on atrium (hydrodynamics and rheology) JF - bioRxiv DO - 10.1101/037705 SP - 037705 AU - Yuri Kamnev Y1 - 2016/01/01 UR - http://biorxiv.org/content/early/2016/01/22/037705.abstract N2 - The precision of the inlet parameters depends on mechanism of response. Reflexes are satisfied with relative higher or lower but if the inlet information is presented by different parameters and the response is calculated according to some equation precision must reach the degree which does not slur over the results of calculation. At recent work the equation for controlling of circulation was suggested where the main inlet parameters are the arterial diastolic and vinous pressures and it becomes pertinent to analyze how organism can perceive these pressures with hydrodynamic accuracy. As far as the velocity pressure component of total pressure can not be detected by wall receptor of the rectilinear section of artery it was noticed that baroreceptors are located at the outer radius of the bend of central arteries and that is justified due to specific distribution of pressure. This phenomenon can be interpreted as a correction of measuring of static pressure with regard for velocity pressure component. Velocity pressure component of venous pressure is comparable with the one of arterial pressure but static components of venous and arterial pressures are incomparable and it is the fact that cannot be ignored when choosing the gauge. The possible method of measuring of pressure is based on observation that pressure-volume vector of the ventricular cycle is similar to a-loop vector of atrial cycle. Ventricular filling vector and x-trough vector show the behavior of viscous material but v-loop inserted into a-loop demonstrates typical viscoelasticity with creep. If viscous deformation of atrium at early relaxation possesses standard duration being stopped by transformation of viscous deformation into viscoelastic deformation the venous pressure can be measured in accordance with the value of viscous deformation. Measuring of pressure by viscous method implemented by atrium has the advantage comparing to measuring by baroreceptor with elastic sensor. Early relaxation of atrium which reveals coefficient of viscosity corresponds to ventricular relaxation and its coefficient of viscosity but the latter is liable to different biochemical shifts. Such shifts influences the atrial coefficient of viscosity either and the values of venous pressure measured by viscous method will be more accurate for calculations because coefficient of viscosity participates in the equation being not estimated in organism. ER -