RT Journal Article SR Electronic T1 Adenita: Interactive 3D modeling and visualization of DNA Nanostructures JF bioRxiv FD Cold Spring Harbor Laboratory SP 849976 DO 10.1101/849976 A1 de Llano, Elisa A1 Miao, Haichao A1 Ahmadi, Yasaman A1 Wilson, Amanda J. A1 Beeby, Morgan A1 Viola, Ivan A1 Barisic, Ivan YR 2019 UL http://biorxiv.org/content/early/2019/11/29/849976.abstract AB We present Adenita, a novel software tool for the design of DNA nanostructures in a user-friendly integrated environment for molecular modeling. Adenita is capable of handling large DNA origami structures, re-use them as building blocks of new designs and provide on demand feedback, thus overcoming effectively some of the limitations of existing tools. Additionally, it integrates all major established approaches to DNA nanostructure design (DNA origami, wireframe nanostructures and DNA tiles) and allows to combine them. We show-case Adenita by re-using a large nanorod designed with Cadnano [1] to create a new nanostructure through user interactions that employ different editors to modify the original nanorod.