RT Journal Article
SR Electronic
T1 Adenita: Interactive 3D modeling and visualization of DNA Nanostructures
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 849976
DO 10.1101/849976
A1 de Llano, Elisa
A1 Miao, Haichao
A1 Ahmadi, Yasaman
A1 Wilson, Amanda J.
A1 Beeby, Morgan
A1 Viola, Ivan
A1 Barisic, Ivan
YR 2019
UL http://biorxiv.org/content/early/2019/11/29/849976.abstract
AB We present Adenita, a novel software tool for the design of DNA nanostructures in a user-friendly integrated environment for molecular modeling. Adenita is capable of handling large DNA origami structures, re-use them as building blocks of new designs and provide on demand feedback, thus overcoming effectively some of the limitations of existing tools. Additionally, it integrates all major established approaches to DNA nanostructure design (DNA origami, wireframe nanostructures and DNA tiles) and allows to combine them. We show-case Adenita by re-using a large nanorod designed with Cadnano [1] to create a new nanostructure through user interactions that employ different editors to modify the original nanorod.