PT - JOURNAL ARTICLE AU - E. Coissac AU - C. Gonindard-Melodelima TI - Assessing the shared variation among high-dimensional data matrices: a modified version of the Procrustean correlation coefficient AID - 10.1101/842070 DP - 2019 Jan 01 TA - bioRxiv PG - 842070 4099 - http://biorxiv.org/content/early/2019/12/09/842070.short 4100 - http://biorxiv.org/content/early/2019/12/09/842070.full AB - Motivation Molecular biology and ecology studies can produce high dimension data. Estimating correlations and shared variation between such data sets are an important step in disentangling the relationships between different elements of a biological system. Unfortunately, classical approaches are susceptible to producing falsely inferred correlations.Results Here we propose a corrected version of the Procrustean correlation coefficient that is robust to high dimensional data. This allows for a correct estimation of the shared variation between two data sets and the partial correlation coefficients between a set of matrix data.Availability The proposed corrected coefficients are implemented in the ProcMod R package available on CRAN. The git repository is hosted at https://git.metabarcoding.org/lecasofts/ProcModContact eric.coissac{at}metabarcoding.org