PT  - JOURNAL ARTICLE
AU  - Mélanie Massonnet
AU  - Noé Cochetel
AU  - Andrea Minio
AU  - Amanda M. Vondras
AU  - Aline Muyle
AU  - Jerry Lin
AU  - Jadran F. Garcia
AU  - Yongfeng Zhou
AU  - Massimo Delledonne
AU  - Summaira Riaz
AU  - Rosa Figueroa-Balderas
AU  - Brandon S. Gaut
AU  - Dario Cantu
TI  - The genetic basis of sex determination in grapevines (<em>Vitis spp.</em>)
AID  - 10.1101/2019.12.11.861377
DP  - 2019 Jan 01
TA  - bioRxiv
PG  - 2019.12.11.861377
4099  - http://biorxiv.org/content/early/2019/12/12/2019.12.11.861377.short
4100  - http://biorxiv.org/content/early/2019/12/12/2019.12.11.861377.full
AB  - Sex determination in grapevine evolved through a complex succession of switches in sexual systems. Phased genomes built with single molecule real-time sequencing reads were assembled for eleven accessions of cultivated hermaphrodite grapevines and dioecious males and females, including the ancestor of domesticated grapevine and other related wild species. By comparing the phased sex haplotypes, we defined the sex locus of the Vitis genus and identified polymorphisms spanning regulatory and coding sequences that are in perfect association with each sex-type throughout the genus. These findings identified a novel male-fertility candidate gene, INP1, and significantly refined the model of sex determination in Vitis and its evolution.