PT - JOURNAL ARTICLE AU - Arnold, Pieter A. AU - Levin, Samantha AU - Stevanovic, Aleksej L. AU - Johnson, Karyn N. TI - <em>Wolbachia</em>-infected <em>Drosophila</em> prefer cooler temperatures AID - 10.1101/352872 DP - 2018 Jan 01 TA - bioRxiv PG - 352872 4099 - http://biorxiv.org/content/early/2018/06/21/352872.short 4100 - http://biorxiv.org/content/early/2018/06/21/352872.full AB - Temperature plays a fundamental role in host-pathogen interactions. Wolbachia is an endosymbiont that infects about 40% of arthropod species, which can affect host behaviour and reproduction. The effect of Wolbachia on host thermoregulatory behaviour is largely unknown. Here, we used a thermal gradient to test whether Drosophila melanogaster infected with Wolbachia exhibit different temperature preferences (Tp) to uninfected flies. We found that Wolbachia-infected flies preferred a cooler mean temperature (Tp = 25.06±0.25°C) than uninfected flies (Tp = 25.78±0.24°C). Our finding suggests that Wolbachia-infected hosts might seek out cooler microclimates to reduce exposure to and lessen the consequences of high temperatures.AbbreviationsTbbody temparatureTppreferred temperature