PT - JOURNAL ARTICLE ED - , TI - Clinico-Demographic trend of HIV-positive cases and sero-discordance at a secondary level hospital in Haryana, North India-programmatic implications for a low HIV prevalence State AID - 10.1101/356881 DP - 2018 Jan 01 TA - bioRxiv PG - 356881 4099 - http://biorxiv.org/content/early/2018/06/30/356881.short 4100 - http://biorxiv.org/content/early/2018/06/30/356881.full AB - Background Appropriate programmatic intervention for HIV Care and Treatment in a low prevalence state requires local level analysis of programme data. Data generated at an Integrated Counseling and Testing Centre (ICTC) may provide crucial information to understand the epidemiology of the disease in a particular region. There is paucity of information on HIV epidemiology at sub-district level in a low HIV prevalence State of India.Methods A secondary analysis of the records from January to December for the years, 2009 through 2014 was conducted among clients who tested HIV positive at the ICTC of a sub-district hospital in Haryana, North India.Results A total of 199 individuals were tested HIV positive of whom 121 (61%) were males. By age-group, 8, 8, 178, and 5 individuals were respectively in <5, 5-18, 18-59 and >60 years of age. Over years from 2009 through 2014, 11, 12, 30, 37, 51 and 58 people tested HIV positive, with no sigfinicant sex difference (chi2 p =0.929). Statistically non-significant increase of 18-59 years individuals was observed, from zero in 2009 to 5 in 2014. Major route of transmission was heterosexual (80%), followed-by, parent-to-child (5%), Blood Transfusion (1.5%), MSM (1%) and FSW (0.5%). One third each, were self-referred, from government facility; 16% from tuberculosis clinic. Median CD4 count in 2014, was 392. Serodiscordance rate spouses of HIV positive females was 17%, of males was 33%.Conclusion Analysis of programme data at a sub-district ICTC could highlight emerging trend even in a low HIV prevalence state.