RT Journal Article
SR Electronic
T1 Interspecific variation of olfactory preferences in flies, mice, and humans
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 358713
DO 10.1101/358713
A1 Diogo Manoel
A1 Melanie Makhlouf
A1 Antonio Scialdone
A1 Luis R. Saraiva
YR 2018
UL http://biorxiv.org/content/early/2018/07/03/358713.abstract
AB Aiming to unravel interspecific differences in olfactory preferences, we performed comparative studies of odor valence in flies, mice, and humans. Our analysis revealed that odor preferences of flies correlate positively with the ones of mice and negatively with the ones of humans, but found no evidence supporting the hypothesis that humans and mice prefer the same odors. We further find that odorants eliciting the highest and lowest preferences are often advertising critical biological sources (e.g., food or oviposition sites), suggesting that evolutionary pressures reflecting the ecological needs of each species shape olfactory preferences.