TY - JOUR T1 - MetaCycle: an integrated R package to evaluate periodicity in large scale data JF - bioRxiv DO - 10.1101/040345 SP - 040345 AU - Gang Wu AU - Ron C. Anafi AU - Michael E. Hughes AU - Karl Kornacker AU - John B. Hogenesch Y1 - 2016/01/01 UR - http://biorxiv.org/content/early/2016/02/19/040345.abstract N2 - Summary: Detecting periodicity in large scale data remains a challenge. Different algorithms offer strengths and weaknesses in statistical power, sensitivity to outliers, ease of use, and sampling requirements. While efforts have been made to identify best of breed algorithms, relatively little research has gone into integrating these methods in a generalizable method. Here we present MetaCycle, an R package that incorporates ARSER, JTK_CYCLE, and Lomb-Scargle to conveniently evaluate periodicity in time-series data.Availability and implementation: MetaCycle package is available on the CRAN repository (https://cran.r-project.org/web/packages/MetaCycle/index.html) and GitHub (https://github.com/gangwug/MetaCycle).Contact: hogenesch{at}gmail.comSupplementary information: Supplementary data are available at Bioinformatics online. ER -