PT  - JOURNAL ARTICLE
AU  - Robert L. McGrath
AU  - Melissa L. Ziegler
AU  - Margaret Pires-Fernandes
AU  - Brian A. Knarr
AU  - Jill S. Higginson
AU  - Fabrizio Sergi
TI  - The effect of stride length on lower extremity joint kinetics at various gait speeds
AID  - 10.1101/363788
DP  - 2018 Jan 01
TA  - bioRxiv
PG  - 363788
4099  - http://biorxiv.org/content/early/2018/07/06/363788.short
4100  - http://biorxiv.org/content/early/2018/07/06/363788.full
AB  - Robot-assisted training is a promising tool under development for rehabilitation of walking function following neurological injury. The challenges in developing the controllers for gait rehabilitation devices that promote desired changes in gait is complicated by the limited understanding of the human response to robotic input. A possible method of controller formulation can be based on the principle of bio-inspiration, where a robot is controlled to apply the change in joint moment applied by human subjects when they achieve a gait feature of interest. However, it is currently unclear how lower extremity joint moments are modulated by even basic gait spatio-temporal parameters.In this study, we investigated how sagittal plane joint moments are affected by a factorial modulation of two important gait parameters: gait speed and stride length. We present the findings obtained from 20 healthy control subjects walking at various treadmill-imposed speeds and instructed to modulate stride length utilizing real-time visual feedback. Implementing a continuum analysis of inverse-dynamics derived joint moment profiles, we extracted the global effects of gait speed and stride length on joint moment throughout the gait cycle. Moreover, we utilized a torque pulse approximation analysis to determine the timing and amplitude of torque pulses that approximate the difference in joint moment profiles between stride length conditions, at all gait speed conditions.Our results show that gait speed has a significant effect on the moment profiles in all joints considered, while stride length has more localized effects, with the main effect observed on the knee moment during stance, and smaller effects observed for the hip joint moment during swing and ankle moment during the loading response. Moreover, our study demonstrated that trailing limb angle, a parameter of interest in programs targeting propulsion at push-off, was significantly correlated with stride length. As such, our study has generated candidate assistance strategies based on pulses of torque suitable for implementation via a wearable exoskeleton with the objective of modulating stride length, and other correlated variables such as trailing limb angle.