PT - JOURNAL ARTICLE AU - Po-E Li AU - Chien-Chi Lo AU - Joseph J. Anderson AU - Karen W. Davenport AU - Kimberly A. Bishop-Lilly AU - Yan Xu AU - Sanaa Ahmed AU - Shihai Feng AU - Vishwesh P. Mokashi AU - Patrick S. G. Chain TI - Enabling the democratization of the genomics revolution with a fully integrated web-based bioinformatics platform AID - 10.1101/040477 DP - 2016 Jan 01 TA - bioRxiv PG - 040477 4099 - http://biorxiv.org/content/early/2016/02/21/040477.short 4100 - http://biorxiv.org/content/early/2016/02/21/040477.full AB - Continued advancements in sequencing technologies have fueled the development of new sequencing applications and promise to flood current databases with raw data. A number of factors prevent the seamless and easy use of these data, including the breadth of project goals, the wide array of tools that individually perform fractions of any given analysis, the large number of associated software/hardware dependencies, and the detailed expertise required to perform these analyses. To address these issues, we have developed an intuitive web-based environment with a wide assortment of integrated and cutting-edge bioinformatics tools. These preconfigured workflows provide even novice next-generation sequencing users with the ability to perform many complex analyses with only a few mouse clicks, and, within the context of the same environment, to visualize and further interrogate their results. This bioinformatics platform is an initial attempt at Empowering the Development of Genomics Expertise (EDGE) in a wide range of applications.