RT Journal Article
SR Electronic
T1 Small-scale field assessment of efficacy of the autodissemination approach against Aedes sp. in an urban area
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 2020.01.13.904094
DO 10.1101/2020.01.13.904094
A1 Ahmad Mohiddin Mohd Ngesom
A1 Hidayatulfathi Othman
A1 Rawaida Bahauddin
A1 Nazni Wasi Ahmad
A1 Lee Han Lim
A1 Asmalia Md Lasim
A1 Yanfeng Liang
A1 David Greenhalgh
A1 Jasmine Chia Siew Min
A1 Mazrura Sahani
A1 Rozita Hod
A1 Topek Omar
YR 2020
UL http://biorxiv.org/content/early/2020/01/13/2020.01.13.904094.abstract
AB This is the first study to evaluate the efficacy of an autodissemination approach, as suggested by WHO. Therefore, the efficacy of an autodissemination approach in small-scale field trials against wild Aedes sp. population was evaluated in an urbanized setting, Malaysia. Lethal ovitraps enhanced with pyriproxyfen were used to control Aedes sp. populations at treatment sites, with the autodissemination activity was assessed using the WHO larval bioassays. Lethal ovitraps enhanced with pyriproxyfen effectively reduced of Aedes sp. population. All autodissemination stations were shown to be visited by Aedes sp. mosquitoes with 100% complete inhibition against eggs and larvae development. In the larvae bioassay, pupae mortality ranged from 14 to 40%. Statistically, a significant reduction of Aedes sp. population in the treatment sites compared to the untreated areas. The study proved for the autodissemination of pyriproxyfen to breeding habitats by wild Aedes sp. This technique is highly potentially for vector control activities. Future evaluation should focus on large-scale field trials.Author Summary Since 2012, Dataran Automobil, Seksyen 15, Shah Alam, was declared as one of the dengue hotspot areas. Major vector control activities were conducted by government, NGOs, social communities, and local authorities, but the number still rising. We conducted a new invention of autodissemination concepts in this area by an entomological study on mosquito populations reduction and dispersal abilities of the technique. We found that the technique has proven to control mosquito populations, but the other factors such as epidemiology link still unclear and need further clarification. Our finding highlighted the effectiveness of autodissemination strategies that can be considered as one of the alternative tools in vector control programme.