PT  - JOURNAL ARTICLE
AU  - Edgar, Robert C.
TI  - URMAP, an ultra-fast read mapper
AID  - 10.1101/2020.01.12.903351
DP  - 2020 Jan 01
TA  - bioRxiv
PG  - 2020.01.12.903351
4099  - http://biorxiv.org/content/early/2020/01/14/2020.01.12.903351.short
4100  - http://biorxiv.org/content/early/2020/01/14/2020.01.12.903351.full
AB  - Mapping of reads to reference sequences is an essential step in a wide range of biological studies. The large size of datasets generated with next-generation sequencing technologies motivates the development of fast mapping software. Here, I describe URMAP, a new read mapping algorithm. URMAP is an order of magnitude faster than BWA and Bowtie2 with comparable accuracy on a benchmark test using simulated paired 150nt reads of a well-studied human genome. Software is freely available at https://drive5.com/urmap.