RT Journal Article
SR Electronic
T1 URMAP, an ultra-fast read mapper
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 2020.01.12.903351
DO 10.1101/2020.01.12.903351
A1 Edgar, Robert C.
YR 2020
UL http://biorxiv.org/content/early/2020/01/14/2020.01.12.903351.abstract
AB Mapping of reads to reference sequences is an essential step in a wide range of biological studies. The large size of datasets generated with next-generation sequencing technologies motivates the development of fast mapping software. Here, I describe URMAP, a new read mapping algorithm. URMAP is an order of magnitude faster than BWA and Bowtie2 with comparable accuracy on a benchmark test using simulated paired 150nt reads of a well-studied human genome. Software is freely available at https://drive5.com/urmap.