RT Journal Article
SR Electronic
T1 The draft genome sequence of mandrill (<em>Mandrillus sphinx</em>)
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 367870
DO 10.1101/367870
A1 Ye Yin
A1 Ting Yang
A1 Huan Liu
A1 Ziheng Huang
A1 Yaolei Zhang
A1 Yue Song
A1 Wenliang Wang
A1 Karsten Kristiansen
YR 2018
UL http://biorxiv.org/content/early/2018/07/12/367870.abstract
AB Background Mandrill (Mandrillus sphinx) is a primate species which belong to Old World monkey (Cercopithecidae) family. It is closely related to human, serving as model for some human diseases researches. However, genetic researches and genomic resources of mandrill were limited, especially comparing to other primate species.Findings Here we sequenced 284 Gb data, providing 96-fold coverage (considering the estimate genome size of 2.9 Gb), to construct a reference genome for mandrill. The assembled draft genome was 2.79 Gb with contig N50 of 20.48 Kb and scaffold N50 of 3.56 Mb. We annotated the mandrill genome to find 43.83% repeat elements, as well as 21,906 protein coding genes. We found good quality of the draft genome and gene annotation by BUSCO analysis which revealed 98% coverage of the BUSCOs.Conclusions We established the first draft genome sequence of mandrill, which is valuable resource for future evolutionary and human diseases studies.bpbase pairkbkilo baseGbgiga baseMYAmillion years agoPSMCpairwise sequentially Markovian coalescentTEtransposable elementBUSCOBenchmarking Universal Single-Copy Orthologs