RT Journal Article
SR Electronic
T1 Sleep selectively stabilizes contextual aspects of negative memories
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 370965
DO 10.1101/370965
A1 Roy Cox
A1 Marthe LV van Bronkhorst
A1 Mollie Bayda
A1 Herron Gomillion
A1 Eileen Cho
A1 Elaine Parr
A1 Olivia P Manickas-Hill
A1 Anna C Schapiro
A1 Robert Stickgold
YR 2018
UL http://biorxiv.org/content/early/2018/07/17/370965.abstract
AB Sleep and emotion are both powerful modulators of the long-term stability of episodic memories, but precisely how these factors interact remains unresolved. We assessed changes in item recognition, contextual memory, and affective tone for negative and neutral memories across a 12 h interval containing sleep or wakefulness in 71 human volunteers. Our data indicate a sleep-dependent stabilization of negative contextual memories, in a way not seen for neutral memories, item recognition, or across wakefulness. Furthermore, retention of contextual memories was positively associated with time spent in non-rapid eye movement sleep. Finally, our results offer partial support for the hypothesis that sleep attenuates emotional responses to previously memorized material.