RT Journal Article
SR Electronic
T1 Horizontal transfer in bacterial Methionyl tRNA synthetase is very common shown by Genus and phyla level phylogenetic analysis
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 042366
DO 10.1101/042366
A1 Prabhakar B. Ghorpade
A1 Avinash D. Pange
A1 Bhaskar Sharma
YR 2016
UL http://biorxiv.org/content/early/2016/03/06/042366.abstract
AB Methionyl tRNA synthetase is single copy informational gene in Salmonella typhimurium. Informational genes are more conserved than operational genes. In this study we had analyzed HGT events within MetG sequences of different bacterial genera. A species tree based on 16srRNA sequences of the same genus was drawn evaluated against the generally accepted species tree of the bacteria. MetG phylogenetic tree was evaluated against the 16srRNAS tree and HGT event identified. Similarly phyla trees were made and HGT event identified. 24 HGT events were identified between genus and 11 within phyla. MetG is a considered as conserved gene finding so many HGT event in this gene indicate that horizontal gene transfer is very common in this gene. Manual tree making for phyla could help to understand phylogenetic relationships between very large trees.