RT Journal Article
SR Electronic
T1 Transparent and flexible ECoG electrode arrays based on silver nanowire networks for neural recordings
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 2020.02.24.962878
DO 10.1101/2020.02.24.962878
A1 Joana P. Neto
A1 Adriana Costa
A1 Joana Vaz Pinto
A1 André Marques–Smith
A1 Júlio Costa
A1 Rodrigo Martins
A1 Elvira Fortunato
A1 Adam Kampff
A1 Pedro Barquinha
YR 2020
UL http://biorxiv.org/content/early/2020/02/25/2020.02.24.962878.abstract
AB This work explored hybrid films of silver nanowires (AgNWs) with indium-doped zinc oxide (IZO) for developing high-performance and low-cost electrocorticography (ECoG) electrodes.The hybrid films achieved a sheet resistance of 6 Ω/sq while maintaining a transparency of ≈60% at 550 nm. Electrodes with 500 μm diameter were fabricated with these films and reached an impedance of 20 kΩ at 1 kHz and a charge storage capacity of 3.2 mC/cm2, a 2× and 320× improvement over IZO electrodes, respectively. Characterization of light-induced artifacts was performed showing that small light intensities (<14 mW/mm2) elicit electrical potential variation in the magnitude order of baseline noise. The validation of electrodes in vivo was achieved by recording electrical neural activity from the surface of rat cortex under anaesthesia. Moreover, the presence of the films did not cause obstruction of light during fluorescence microscopy.The presented film and electrode characterization studies highlighted the capabilities of this hybrid structure to fabricate transparent and flexible electrodes that are able to combine the superior temporal resolution of extracellular electrophysiology with the spatial resolution offered by optical imaging.