PT  - JOURNAL ARTICLE
AU  - Amanda M. Casto
AU  - Meei-Li Huang
AU  - Hong Xie
AU  - Keith R. Jerome
AU  - Anna Wald
AU  - Christine Johnston
AU  - Alexander L. Greninger
TI  - Herpes Simplex Virus Mistyping due to HSV-1 x HSV-2 Interspecies Recombination in Viral Gene Encoding Glycoprotein B
AID  - 10.1101/2020.02.25.965426
DP  - 2020 Jan 01
TA  - bioRxiv
PG  - 2020.02.25.965426
4099  - http://biorxiv.org/content/early/2020/02/26/2020.02.25.965426.short
4100  - http://biorxiv.org/content/early/2020/02/26/2020.02.25.965426.full
AB  - Human herpes simplex viruses (HSV) 1 and 2 are most often typed via molecular assays. Here we describe the first known case of HSV mistyping due to a previously undescribed HSV-1 x HSV-2 recombination event in UL27, the gene that encodes glycoprotein B. This is the first reported HSV interspecies recombination event impacting this gene, which is frequently used as a target for diagnostics and experimental therapeutics.