PT  - JOURNAL ARTICLE
AU  - Steinegger, Martin
AU  - Mirdita, Milot
AU  - Söding, Johannes
TI  - Protein-level assembly increases protein sequence recovery from metagenomic samples manyfold
AID  - 10.1101/386110
DP  - 2018 Jan 01
TA  - bioRxiv
PG  - 386110
4099  - http://biorxiv.org/content/early/2018/08/07/386110.short
4100  - http://biorxiv.org/content/early/2018/08/07/386110.full
AB  - The open-source de-novo Protein-Level ASSembler Plass (https://plass.mmseqs.org) assembles six-frame-translated sequencing reads into protein sequences. It recovers 2 to 10 times more protein sequences from complex metagenomes and can assemble huge datasets. We assembled two redundancy-filtered reference protein catalogs, 2 billion sequences from 640 soil samples (SRC) and 292 million sequences from 775 marine eukaryotic metatranscriptomes (MERC), the largest free collections of protein sequences.