PT  - JOURNAL ARTICLE
AU  - Wang, Chunyan
AU  - Li, Wentao
AU  - Drabek, Dubravka
AU  - Okba, Nisreen M.A.
AU  - van Haperen, Rien
AU  - Osterhaus, Albert D.M.E.
AU  - van Kuppeveld, Frank J.M.
AU  - Haagmans, Bart L.
AU  - Grosveld, Frank
AU  - Bosch, Berend-Jan
TI  - A human monoclonal antibody blocking SARS-CoV-2 infection
AID  - 10.1101/2020.03.11.987958
DP  - 2020 Jan 01
TA  - bioRxiv
PG  - 2020.03.11.987958
4099  - http://biorxiv.org/content/early/2020/03/12/2020.03.11.987958.short
4100  - http://biorxiv.org/content/early/2020/03/12/2020.03.11.987958.full
AB  - The emergence of the novel human coronavirus SARS-CoV-2 in Wuhan, China has caused a worldwide epidemic of respiratory disease (COVID-19). Vaccines and targeted therapeutics for treatment of this disease are currently lacking. Here we report a human monoclonal antibody that neutralizes SARS-CoV-2 (and SARS-CoV). This cross-neutralizing antibody targets a communal epitope on these viruses and offers potential for prevention and treatment of COVID-19.