RT Journal Article
SR Electronic
T1 Efficient inactivation of SARS-CoV-2 by WHO-recommended hand rub formulations and alcohols
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 2020.03.10.986711
DO 10.1101/2020.03.10.986711
A1 Kratzel, Annika
A1 Todt, Daniel
A1 V’kovski, Philip
A1 Steiner, Silvio
A1 Gultom, Mitra L.
A1 Thao, Tran Thi Nhu
A1 Ebert, Nadine
A1 Holwerda, Melle
A1 Steinmann, Jörg
A1 Niemeyer, Daniela
A1 Dijkman, Ronald
A1 Kampf, Günter
A1 Drosten, Christian
A1 Steinmann, Eike
A1 Thiel, Volker
A1 Pfaender, Stephanie
YR 2020
UL http://biorxiv.org/content/early/2020/03/17/2020.03.10.986711.abstract
AB The recent emergence of Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing COVID-19 is a major burden for health care systems worldwide. It is important to address if the current infection control instructions based on active ingredients are sufficient. We therefore determined the virucidal activity of two alcohol-based hand rub solutions for hand disinfection recommended by the World Health Organization (WHO), as well as commercially available alcohols. Efficient SARS-CoV-2 inactivation was demonstrated for all tested alcohol-based disinfectants. These findings show the successful inactivation of SARS-CoV-2 for the first time and provide confidence in its use for the control of COVID-19.Importance The current COVID-19 outbreak puts a huge burden on the world’s health care systems. Without effective therapeutics or vaccines being available, effective hygiene measure are of utmost importance to prevent viral spreading. It is therefore crucial to evaluate current infection control strategies against SARS-CoV-2. We show the inactivation of the novel coronavirus for the first time and endorse the importance of disinfectant-based hand hygiene to reduce SARS-CoV-2 transmission.