PT  - JOURNAL ARTICLE
AU  - Stephen M. Canham
AU  - Yuan Wang
AU  - Allen Cornett
AU  - Douglas S. Auld
AU  - Daniel K. Baeschlin
AU  - Maude Patoor
AU  - Philip R. Skaanderup
AU  - Ayako Honda
AU  - Luis Llamas
AU  - Greg Wendel
AU  - Felipa A. Mapa
AU  - Peter Aspesi, Jr.
AU  - Nancy Labbe-Giguere
AU  - Gabriel G. Gamber
AU  - Daniel S. Palacios
AU  - Ansgar Schuffenhauer
AU  - Zhan Deng
AU  - Florian Nigsch
AU  - Mathias Frederiksen
AU  - Simon M. Bushell
AU  - Deborah Rothman
AU  - Rishi K. Jain
AU  - Horst Hemmerle
AU  - Karin Briner
AU  - Jeffery A. Porter
AU  - John A. Tallarico
AU  - Jeremy L. Jenkins
TI  - Systematic Chemogenetic Library Assembly
AID  - 10.1101/2020.03.30.017244
DP  - 2020 Jan 01
TA  - bioRxiv
PG  - 2020.03.30.017244
4099  - http://biorxiv.org/content/early/2020/04/01/2020.03.30.017244.short
4100  - http://biorxiv.org/content/early/2020/04/01/2020.03.30.017244.full
AB  - The assembly of chemogenetic libraries composed of chemical probes provides tremendous value to biomedical research, but requires substantial effort to ensure diversity as well as quality of the contents. We are assembling a chemogenetic library by data mining and crowdsourcing institutional expertise. We are sharing our methodology, lessons learned, and disclosing our current collection of 4186 compounds with their primary annotated gene targets.