PT - JOURNAL ARTICLE AU - Daniel Domingo-Fernández AU - Shounak Baksi AU - Bruce Schultz AU - Yojana Gadiya AU - Reagon Karki AU - Tamara Raschka AU - Christian Ebeling AU - Martin Hofmann-Apitius AU - Alpha Tom Kodamullil TI - COVID-19 Knowledge Graph: a computable, multi-modal, cause-and-effect knowledge model of COVID-19 pathophysiology AID - 10.1101/2020.04.14.040667 DP - 2020 Jan 01 TA - bioRxiv PG - 2020.04.14.040667 4099 - http://biorxiv.org/content/early/2020/04/15/2020.04.14.040667.short 4100 - http://biorxiv.org/content/early/2020/04/15/2020.04.14.040667.full AB - Summary The past few weeks have witnessed a worldwide mobilization of the research community in response to the novel coronavirus (COVID-19). This global response has led to a burst of publications on the pathophysiology of the virus, yet without coordinated efforts to organize this knowledge, it can remain hidden away from individual research groups. By extracting and formalizing this knowledge in a structured and computable form, as in the form of a knowledge graph, researchers can readily reason and analyze this information on a much larger scale. Here, we present the COVID-19 Knowledge Graph, an expansive cause-and-effect network constructed from scientific literature on the new coronavirus that aims to provide a comprehensive view of its pathophysiology. To make this resource available to the research community and facilitate its exploration and analysis, we also implemented a web application and released the KG in multiple standard formats.Availability The COVID-19 Knowledge Graph is publicly available under CC-0 license at https://github.com/covid19kg and https://bikmi.covid19-knowledgespace.de.Contact alpha.tom.kodamullil{at}scai.fraunhofer.deSupplementary information Supplementary data are available online.Competing Interest StatementThe authors have declared no competing interest.