RT Journal Article
SR Electronic
T1 The PCR Simulator: an on-line application for teaching Design of Experiments and the polymerase chain reaction
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 415042
DO 10.1101/415042
A1 Harold Fellermann
A1 Ben Shirt-Ediss
A1 Jerzy W. Koryza
A1 Matthew Linsley
A1 Dennis W. Lendrem
A1 Thomas P. Howard
YR 2018
UL http://biorxiv.org/content/early/2018/09/14/415042.abstract
AB Our PCR Simulator is a web-based application designed to introduce concepts of multi-factorial experimental design and support teaching of the polymerase chain reaction. Learners select experimental settings and receive results of their simulated reactions quickly, allowing rapid iteration between data generation and analysis. This enables the student to perform complex iterative experimental design strategies within a short teaching session. Here we provide a short overview of the user interface and underpinning model, and describe our experience using this tool in a teaching environment.