RT Journal Article SR Electronic T1 MMseqs2 desktop and local web server app for fast, interactive sequence searches JF bioRxiv FD Cold Spring Harbor Laboratory SP 419895 DO 10.1101/419895 A1 Mirdita, Milot A1 Steinegger, Martin A1 Söding, Johannes YR 2018 UL http://biorxiv.org/content/early/2018/09/18/419895.abstract AB The MMseqs2 desktop and web server app facilitates interactive sequence searches through custom protein sequence and profile databases on personal workstations. By eliminating MMseqs2’s runtime overhead, we reduced response times to a few seconds at sensitivities close to BLAST.Availability and implementation The app is easy to install for non-experts. Source code, prebuilt desktop app packages for Windows, macOS and Linux, Docker images for the web server application, and a demo web server are available at https://search.mmseqs.com.Contact martin.steinegger{at}mpibpc.mpg.de or soeding{at}mpibpc.mpg.de