RT Journal Article
SR Electronic
T1 Generation of four iPSC lines from peripheral blood mononuclear cells (PBMCs) of an Attention Deficit Hyperactivity Disorder (ADHD) individual and a healthy sibling in an Australia-Caucasian family
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 420505
DO 10.1101/420505
A1 Janette Tong
A1 Kyung Min Lee
A1 Xiaodong Liu
A1 Christian M Nefzger
A1 Prasidhee Vijayakumar
A1 Ziarih Hawi
A1 Ken C Pang
A1 Clare L Parish
A1 Jose M Polo
A1 Mark A Bellgrove
YR 2018
UL http://biorxiv.org/content/early/2018/09/18/420505.abstract
AB Peripheral blood mononuclear cells were donated by a male teenager with clinically diagnosed Attention Deficit Hyperactivity Disorder under the Diagnostic and Statistical Manual of Mental Disorders IV criteria and his unaffected male sibling. Induced pluripotent stem cells were developed using integration-free Sendai Reprogramming factors containing OCT, SOX2, KLF4, and c-MYC. All four iPSC lines displayed pluripotent cell morphology, pluripotency-associated factors at protein level, alkaline phosphatase enzymatic activity, male karyotype of 46, XY, and in vitro differentiation capacity into all the three germ layers and negative for Mycoplasma.