PT  - JOURNAL ARTICLE
AU  - Harold Fellermann
AU  - Ben Shirt-Ediss
AU  - Jerzy W. Koryza
AU  - Matthew Linsley
AU  - Dennis W. Lendrem
AU  - Thomas P. Howard
TI  - The PCR Simulator: an on-line application for teaching Design of Experiments and the polymerase chain reaction
AID  - 10.1101/415042
DP  - 2018 Jan 01
TA  - bioRxiv
PG  - 415042
4099  - http://biorxiv.org/content/early/2018/09/18/415042.short
4100  - http://biorxiv.org/content/early/2018/09/18/415042.full
AB  - Our PCR Simulator is a web-based application designed to introduce concepts of multi-factorial experimental design and support teaching of the polymerase chain reaction. Learners select experimental settings and receive results of their simulated reactions quickly, allowing rapid iteration between data generation and analysis. This enables the student to perform complex iterative experimental design strategies within a short teaching session. Here we provide a short overview of the user interface and underpinning model, and describe our experience using this tool in a teaching environment.