RT Journal Article SR Electronic T1 The complete genome sequence of the Staphylococcus bacteriophage Metroid JF bioRxiv FD Cold Spring Harbor Laboratory SP 2020.05.01.072256 DO 10.1101/2020.05.01.072256 A1 Adele Crane A1 Joy Abaidoo A1 Gabriella Beltran A1 Danielle Fry A1 Colleen Furey A1 Noe Green A1 Ravneet Johal A1 Bruno La Rosa A1 Catalina Lopez Jimenez A1 Linh Luong A1 Garett Maag A1 Jade Porche A1 Lauren Reyes A1 Aspen Robinson A1 Samantha Sabbara A1 Lucia Soto Herrera A1 Angelica Urquidez Negrete A1 Pauline Wilson A1 Kerry Geiler-Samerotte A1 Susanne P. Pfeifer YR 2020 UL http://biorxiv.org/content/early/2020/05/01/2020.05.01.072256.abstract AB Phages infecting bacteria of the genus Staphylococcus play an important role in their host’s ecology and evolution. On one hand, horizontal gene transfer from phage can encourage the rapid adaptation of pathogenic Staphylococcus enabling them to escape host immunity or access novel environments. On the other hand, lytic phages are promising agents for the treatment of bacterial infections, especially those resistant to antibiotics. As part of an ongoing effort to gain novel insights into bacteriophage diversity, we characterized the complete genome of the Staphylococcus bacteriophage Metroid, a cluster C phage with a genome size of 151kb, encompassing 254 predicted protein-coding genes as well as 4 tRNAs. A comparative genomic analysis highlights strong similarities – including a conservation of the lysis cassette – with other Staphylococcus cluster C1 bacteriophages, several of which were previously characterized for therapeutic applications.Competing Interest StatementThe authors have declared no competing interest.