RT Journal Article
SR Electronic
T1 Phase-amplitude coupling profiles differ in frontal and auditory cortices
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 2020.05.05.078667
DO 10.1101/2020.05.05.078667
A1 Francisco García-Rosales
A1 Luciana López-Jury
A1 Eugenia González-Palomares
A1 Yuranny Cabral-Calderin
A1 Manfred Kössl
A1 Julio C. Hechavarria
YR 2020
UL http://biorxiv.org/content/early/2020/05/06/2020.05.05.078667.abstract
AB Neural oscillations are at the core of important computations in the mammalian brain. Interactions between oscillatory activities in different frequency bands, such as delta (1-4 Hz), theta (4-8 Hz), or gamma (>30 Hz), are a powerful mechanism for binding fundamentally distinct spatiotemporal scales of neural processing. Phase-amplitude coupling (PAC) is one such plausible and well-described interaction, but much is yet to be uncovered regarding how PAC dynamics contribute to sensory representations. In particular, although PAC appears to have a major role in audition, the characteristics of coupling profiles in sensory and integration (i.e. frontal) cortical areas remain obscure. Here, we address this question by studying PAC dynamics in the frontal-auditory field (FAF; an auditory area in the bat frontal cortex) and the auditory cortex (AC) of the bat Carollia perspicillata. By means of simultaneous electrophysiological recordings in frontal and auditory cortices examining local-field potentials (LFPs), we show that the amplitude of gamma-band activity couples with the phase of low-frequency LFPs in both structures. Our results demonstrate that the coupling in FAF occurs most prominently in delta/high-gamma frequencies (1-4/75-100 Hz), whereas in the AC the coupling is strongest in the theta/low-gamma (2-8/25-55 Hz) range. We argue that distinct PAC profiles may represent different mechanisms for neuronal processing in frontal and auditory cortices, and might complement oscillatory interactions for sensory processing in the frontal-auditory cortex network.Competing Interest StatementThe authors have declared no competing interest.