PT - JOURNAL ARTICLE AU - Takuma Sugi AU - Etsuko Okumura AU - Kaori Kiso AU - Ryuji Igarashi TI - Nanoscale mechanical stimulation method for quantifying <em>C. elegans</em> mechanosensory behavior and memory AID - 10.1101/047431 DP - 2016 Jan 01 TA - bioRxiv PG - 047431 4099 - http://biorxiv.org/content/early/2016/04/06/047431.short 4100 - http://biorxiv.org/content/early/2016/04/06/047431.full AB - Here, we establish a novel economic system to quantify C. elegans mechanosensory behavior and memory by a controllable nanoscale mechanical stimulation. Using piezoelectric sheet speaker, we can flexibly change the vibration properties at a nanoscale displacement level and quantify behavioral responses and memory under the control of each vibration property. This system will facilitate understanding of physiological aspects of C. elegans mechanosensory behavior and memory.