RT Journal Article
SR Electronic
T1 Cortical suppressive waves shape the representation of long-range apparent motion
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 372763
DO 10.1101/372763
A1 S Chemla
A1 A Reynaud
A1 M di Volo
A1 Y Zerlaut
A1 L Perrinet
A1 A Destexhe
A1 F Chavane
YR 2018
UL http://biorxiv.org/content/early/2018/10/09/372763.abstract
AB How does the brain link visual stimuli across space and time? Visual illusions provide an experimental paradigm to study these processes. When two stationary dots are flashed in close spatial and temporal succession, human observers experience a percept of motion. Large spatio-temporal separation challenges the visual system to keep track of object identity along the apparent motion path. Here, we utilize voltage-sensitive dye imaging in primary visual cortex (V1) of the awake monkey to investigate whether intra-cortical connections within V1 can shape cortical dynamics to represent the illusory motion. We find that the arrival of the second stimulus in V1 creates a suppressive wave traveling toward the retinotopic representation of the first. Computational approaches show that this suppressive wave can be explained by recurrent gain control fed by the intra-cortical network and contributes to precisely encode the expected motion velocity. We suggest that non-linear intra-cortical dynamics preformat population responses in V1 for optimal read-out by downstream areas.