RT Journal Article
SR Electronic
T1 <em>coronapp</em>: A Web Application to Annotate and Monitor SARS-CoV-2 Mutations
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 2020.05.31.124966
DO 10.1101/2020.05.31.124966
A1 Daniele Mercatelli
A1 Luca Triboli
A1 Eleonora Fornasari
A1 Forest Ray
A1 Federico M. Giorgi
YR 2020
UL http://biorxiv.org/content/early/2020/06/01/2020.05.31.124966.abstract
AB The avalanche of genomic data generated from the SARS-CoV-2 virus requires the development of tools to detect and monitor its mutations across the World. Here, we present a webtool, coronapp, dedicated to easily processing user-provided SARS-CoV-2 genomic sequences, in order to detect and annotate protein-changing mutations. This results in an up-to-date status of SARS-CoV-2 mutations, both worldwide and in user-selected countries. The tool allows users to highlight and prioritize the most frequent mutations in specific protein regions, and to monitor their frequency in the population over time.The tool is available at http://giorgilab.dyndns.org/coronapp/ and the full code is freely shared at https://github.com/federicogiorgi/giorgilab/tree/master/coronappCompeting Interest StatementThe authors have declared no competing interest.