TY - JOUR T1 - COVIDep platform for real-time reporting of vaccine target recommendations for SARS-CoV-2: Description and connections with COVID-19 immune responses and preclinical vaccine trials JF - bioRxiv DO - 10.1101/2020.05.23.111385 SP - 2020.05.23.111385 AU - Syed Faraz Ahmed AU - Ahmed A. Quadeer AU - Matthew R. McKay Y1 - 2020/01/01 UR - http://biorxiv.org/content/early/2020/06/04/2020.05.23.111385.abstract N2 - We introduce COVIDep (https://COVIDep.ust.hk), a web-based platform that provides immune target recommendations for guiding SARS-CoV-2 vaccine development. COVIDep implements a protocol that pools together publicly-available genetic data for SARS-CoV-2 and epitope data for SARS-CoV to identify B cell and T cell epitopes that present potential immune targets for SARS-CoV-2. Correspondences between outputs of COVIDep and immune responses recorded in COVID-19 patients and preclinical vaccine trials are also indicated. The platform is user-friendly, flexible, and based on up-to-date data. It may help guide vaccine designs and associated experimental studies for SARS-CoV-2.Competing Interest StatementThe authors have declared no competing interest. ER -