RT Journal Article
SR Electronic
T1 Detection dogs as a help in the detection of COVID-19 Can the dog alert on COVID-19 positive persons by sniffing axillary sweat samples ? Proof-of-concept study
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 2020.06.03.132134
DO 10.1101/2020.06.03.132134
A1 Grandjean, Dominique
A1 Sarkis, Riad
A1 Tourtier, Jean-Pierre
A1 Julien-Lecocq, Clothilde
A1 Benard, Aymeric
A1 Roger, Vinciane
A1 Levesque, Eric
A1 Bernes-Luciani, Eric
A1 Maestracci, Bruno
A1 Morvan, Pascal
A1 Gully, Eric
A1 Berceau-Falancourt, David
A1 Pesce, Jean-Luc
A1 Lecomte, Bernard
A1 Haufstater, Pierre
A1 Herin, Gregory
A1 Cabrera, Joaquin
A1 Muzzin, Quentin
A1 Gallet, Capucine
A1 Bacqué, Hélène
A1 Broc, Jean-Marie
A1 Thomas, Leo
A1 Lichaa, Anthony
A1 Moujaes, Georges
A1 Saliba, Michele
A1 Kuhn, Aurore
A1 Galey, Mathilde
A1 Berthail, Benoit
A1 Lapeyre, Lucien
A1 Méreau, Olivier
A1 Matteï, Marie-Nicolas
A1 Foata, Audrey
A1 Bey, Louisa
A1 Philippe, Anne-Sophie
A1 Abassi, Paul
A1 Pisani, Ferri
A1 Delarbre, Marlène
A1 Orsini, Jean-Marc
A1 Capelli, Anthoni
A1 Renault, Steevens
A1 Bachir, Karim
A1 Kovinger, Anthony
A1 Comas, Eric
A1 Stainmesse, Aymeric
A1 Etienne, Erwan
A1 Voeltzel, Sébastien
A1 Mansouri, Sofiane
A1 Berceau-Falancourt, Marlène
A1 Leva, Brice
A1 Faure, Frederic
A1 Dami, Aimé
A1 Costa, Marc Antoine
A1 Tafanelli, Jean-Jacques
A1 Luciani, Jean-Benoit
A1 Casalot, Jean-Jacques
A1 Charlet, Lary
A1 Ruau, Eric
A1 Issa, Mario
A1 Grenet, Carine
A1 Billy, Christophe
A1 Desquilbet, Loic
YR 2020
UL http://biorxiv.org/content/early/2020/06/05/2020.06.03.132134.abstract
AB The aim of this study is to evaluate if the sweat produced by COVID-19 persons (SARS-CoV-2 PCR positive) has a different odour for trained detection dogs than the sweat produced by non COVID-19 persons. The study was conducted on 3 sites, following the same protocol procedures, and involved a total of 18 dogs. A total of 198 armpits sweat samples were obtained from different hospitals. For each involved dog, the acquisition of the specific odour of COVID-19 sweat samples required from one to four hours, with an amount of positive samples sniffing ranging from four to ten. For this proof of concept, we kept 8 dogs of the initial group (explosive detection dogs and colon cancer detection dogs), who performed a total of 368 trials, and will include the other dogs in our future studies as their adaptation to samples scenting takes more time.The percentages of success of the dogs to find the positive sample in a line containing several other negative samples or mocks (2 to 6) were 100p100 for 4 dogs, and respectively 83p100, 84p100, 90p100 and 94p100 for the others, all significantly different from the percentage of success that would be obtained by chance alone.We conclude that there is a very high evidence that the armpits sweat odour of COVID-19+ persons is different, and that dogs can detect a person infected by the SARS-CoV-2 virus.Competing Interest StatementThe authors have declared no competing interest.