TY - JOUR T1 - Monitoring <em>S. pombe</em> genome stress by visualizing end-binding protein Ku JF - bioRxiv DO - 10.1101/2020.06.12.149054 SP - 2020.06.12.149054 AU - Chance Jones AU - Susan L Forsburg Y1 - 2020/01/01 UR - http://biorxiv.org/content/early/2020/06/12/2020.06.12.149054.abstract N2 - Studies of genome stability have exploited visualization of fluorescently tagged proteins in live cells to characterize DNA damage, checkpoint, and repair responses. In this report, we describe a new tool for fission yeast, a tagged version of the end-binding protein Pku70 which is part of the KU protein complex. We compare Pku70 localization to other markers upon treatment to various genotoxins, and identify a unique pattern of distribution. Pku70 provides a new tool to define and characterize DNA lesions and the repair response. ER -