TY - JOUR T1 - Application of Surgical Lead Management and Reconfigurable Coil Technology to Reduce RF Heating of DBS Implants during MRI at 3T Under Variant Body Compositions JF - bioRxiv DO - 10.1101/2020.06.25.170159 SP - 2020.06.25.170159 AU - Bhumi Bhusal AU - Behzad Elahi AU - Boris Keil AU - Joshua Rosenow AU - Ehsan Kazemivalipour AU - Laleh Golestanirad Y1 - 2020/01/01 UR - http://biorxiv.org/content/early/2020/06/25/2020.06.25.170159.abstract N2 - Patients with active implants such as deep brain stimulation (DBS) devices, have limited access to magnetic resonance imaging (MRI) due to risks of RF heating. With an aging population, the prevalence of neurodegenerative and vascular disease increases; and so does the indication for MRI exams in patients with such implants. In response to this growing need for MRI, many groups have investigated strategies to mitigate the RF heating of the implants. These efforts, however, have relied either on simulations with homogenous body models or simplified phantom experiments (box shaped phantom with single tissue). It is well established, however, that the shape and heterogeneity of human body affects the distribution of MRI electric fields, which by proxy, alters the RF heating of an implant inside the body. In this contribution, we applied numerical simulations and phantom experiments to examine the effectiveness of RF heating mitigation strategies under variant patient body compositions, focusing on two recently proposed techniques: (a) surgical modification of DBS lead trajectories inside the body, and (b) use of a patient-adjustable reconfigurable MRI coil, both aiming to reduce the coupling of implanted leads and MRI electric fields. Our results demonstrated that both techniques perform well under variant body compositions.Competing Interest StatementThe authors have declared no competing interest. ER -