RT Journal Article
SR Electronic
T1 OrthoFinder2: fast and accurate phylogenomic orthology analysis from gene sequences
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 466201
DO 10.1101/466201
A1 D.M., Emms
A1 S., Kelly
YR 2018
UL http://biorxiv.org/content/early/2018/11/08/466201.abstract
AB Ortholog inference has fundamental importance across the biological sciences, underpinning phylogenetics, comparative genomics and prediction of gene function. We developed OrthoFinder (https://github.com/davidemms/OrthoFinder), which achieves higher ortholog recall than all current methods as assessed by community-standard benchmarks. Uniquely, OrthoFinder also infers orthogroups, genes trees, gene duplication events, the rooted species tree and extensive comparative genomic statistics, thus enabling the next generation of phylogenomic analyses.