RT Journal Article
SR Electronic
T1 Body composition and growth in full-term small for gestational age and large for gestational age Swedish infants assessed with air displacement plethysmography at birth and at 3-4 months of age
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 468785
DO 10.1101/468785
A1 Anna Larsson
A1 Peter Ottosson
A1 Caroline Törnqvist
A1 Elisabeth Olhager
YR 2018
UL http://biorxiv.org/content/early/2018/11/12/468785.abstract
AB Background: Being born small for gestational age (SGA) or large for gestational age (LGA) has short and long term metabolic consequences. There is a growing interest in the extent to which body composition, both in the short and the long term, differs in infants born at the extremes of these birth weights.Methods: Body composition in 25 SGA and 25 LGA infants were assessed during the first days of life and at 3-4 months of age using air displacement plethysmography.Results: SGA infants had significantly lower body fat (%) at birth compared to LGA infants. SGA infants increased their body weight and length at a significantly higher rate between birth and 3-4 months than LGA infants. Fat mass (g) in SGA infants increased 23 times between birth and 3-4 months of age compared to 2.8 times for LGA infants. At 3-4 months of age LGA infants reached a threshold in body fat (%) while SGA infants were still gaining body fat (%).Conclusion: Several significant differences have been identified between SGA and LGA infants, indicating that the effects of intrauterine life continues to play an important role in body composition and growth during the first 3-4 months of life.Abbreviations:SGAsmall for gestational ageLGALarge for gestational ageADPair displacement plethysmography