PT  - JOURNAL ARTICLE
AU  - Jianyuan Zhou
AU  - Xuecang Li
AU  - Jiaxin Chen
AU  - Taisong Li
AU  - Weijie Zhan
AU  - Jianmei Zhao
AU  - Meng Li
AU  - Zhengmin Yu
AU  - Rui Yu
AU  - Haiying Zou
AU  - Wangkai Fang
AU  - Qiuyu Wang
AU  - Jianjun Xie
TI  - CATA: a comprehensive chromatin accessibility database for cancer
AID  - 10.1101/2020.05.16.099325
DP  - 2020 Jan 01
TA  - bioRxiv
PG  - 2020.05.16.099325
4099  - http://biorxiv.org/content/early/2020/07/09/2020.05.16.099325.short
4100  - http://biorxiv.org/content/early/2020/07/09/2020.05.16.099325.full
AB  - Chromatin accessibility is a crucial epigenetic concept that plays a biological role in oncology. As humans become more involved in cancer research, a comprehensive database is required to identify and annotate tumor chromatin accessible regions (CARs). Here, CATA was developed to provide cancer-related CAR annotation. Currently, CATA possesses 2,991,163 CARs, relevant clinical data, and transcription factor binding predictions for cancer CARs from 410 tumor samples of 24 cancer types. Furthermore, CARs were annotated by SNPs, risk SNPs, eQTLs, linkage disequilibrium SNPs, transcription factors, CNV, SNV, enhancer, and 450K methylation sites in our database. By combining all these resources, we believe that CATA will provide better service for researchers on oncology. Our database is accessible at http://bio.licpathway.net/cata/Competing Interest StatementThe authors have declared no competing interest.