RT Journal Article
SR Electronic
T1 RefPlantNLR: a comprehensive collection of experimentally validated plant NLRs
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 2020.07.08.193961
DO 10.1101/2020.07.08.193961
A1 Jiorgos Kourelis
A1 Sophien Kamoun
YR 2020
UL http://biorxiv.org/content/early/2020/07/09/2020.07.08.193961.abstract
AB Reference datasets are critical in computational biology. They help define canonical biological features and are essential for benchmarking studies. Here, we describe a comprehensive reference dataset of experimentally validated plant NLR immune receptors. RefPlantNLR consists of 415 NLRs from 31 genera belonging to 11 orders of flowering plants. We used RefPlantNLR to determine the canonical features of functionally validated plant NLRs. This reference dataset should prove useful for benchmarking NLR annotation tools, guiding comparative analyses of NLRs across the wide spectrum of plant diversity and identifying under-studied taxa. We hope that the RefPlantNLR resource will contribute to moving the field beyond a uniform view of NLR structure and function.Competing Interest StatementThe authors receive funding from industry on NLR biology.