PT  - JOURNAL ARTICLE
AU  - Laleh Golestanirad
AU  - Leonardo M Angelone
AU  - John Kirsch
AU  - Sean Downs
AU  - Boris Keil
AU  - Giorgio Bonmassar
AU  - Lawrence L Wald
TI  - Reducing RF-induced Heating near Implanted Leads through High-Dielectric Capacitive Bleeding of Current (CBLOC)
AID  - 10.1101/456533
DP  - 2018 Jan 01
TA  - bioRxiv
PG  - 456533
4099  - http://biorxiv.org/content/early/2018/11/19/456533.short
4100  - http://biorxiv.org/content/early/2018/11/19/456533.full
AB  - Patients with implanted medical devices such as deep brain stimulation or spinal cord stimulation are often unable to receive magnetic resonance imaging (MRI). This is because once the device is within the radiofrequency (RF) field of the MRI scanner, electrically conductive leads act as antenna, amplifying the RF energy deposition in the tissue and causing possible excessive tissue heating. Here we propose a novel concept in lead design in which 40cm lead wires are coated with a ~1.2mm layer of high dielectric constant material (155 < εr < 250) embedded in a weakly conductive insulation (σ = 20 S/m). The technique called High-Dielectric Capacitive Bleeding of Current, or CBLOC, works by forming a distributed capacitance along the lengths of the lead, efficiently dissipating RF energy before it reaches the exposed tip. Measurements during RF exposure at 64 MHz and 123 MHz demonstrated that CBLOC leads generated 20-fold less heating at 1.5 T, and 40-fold less heating at 3 T compared to control leads. Numerical simulations of RF exposure at 297 MHz (7T) predicted a 15-fold reduction in specific absorption rate (SAR) of RF energy around the tip of CBLOC leads compared to control leads.