PT - JOURNAL ARTICLE AU - Ling-Hong Hung AU - Jiaming Hu AU - Trevor Meiss AU - Alyssa Ingersoll AU - Wes Lloyd AU - Daniel Kristiyanto AU - Yuguang Xiong AU - Eric Sobie AU - Ka Yee Yeung TI - Building containerized workflows using the BioDepot-workflow-builder (Bwb) AID - 10.1101/099010 DP - 2018 Jan 01 TA - bioRxiv PG - 099010 4099 - http://biorxiv.org/content/early/2018/11/22/099010.short 4100 - http://biorxiv.org/content/early/2018/11/22/099010.full AB - We present the BioDepot-workflow-builder (Bwb), a software tool that allows users to create and execute reproducible bioinformatics workflows using a drag-and-drop interface. Graphical widgets represent Docker containers executing a modular task. Widgets are then graphically linked to build bioinformatics workflows that can be reproducibly deployed across different local and cloud platforms. Each widget contains a form-based user interface to facilitate parameter entry and a console to display intermediate results. Bwb provides tools for rapid customization of widgets, containers and workflows. Saved workflows can be shared using Bwb’s native format or exported as shell scripts.List of abbreviationsAWS= Amazon Web ServicesBWA= Burroughs-Wheeler AlignerBwb= BioDepot-workflow-BuilderDToxS= Drug Toxicity Signature Generation CenterRNA-seq= RNA sequencingSOP= standard operating procedureVNC= virtual network computing