RT Journal Article
SR Electronic
T1 Seasonal diets overwhelm host species in shaping the gut microbiota of Yak and Tibetan sheep
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 481374
DO 10.1101/481374
A1 Wei, Xiaojuan
A1 Cheng, Fusheng
A1 Shi, Hongmei
A1 Zhou, Xuzheng
A1 Li, Bing
A1 Wang, Ling
A1 Wang, Weiwei
A1 Zhang, Jiyu
YR 2018
UL http://biorxiv.org/content/early/2018/11/29/481374.abstract
AB Host genetics and environmental factors can both shaping composition of gut microbiota, yet which factors are more important is still under debating. Yak (Bos grunniens) and Tibetan sheep (Ovis aries) are very different from the size and genetics. Nomadic Tibetan people keep them as main livestock and feeding them with same grazing systems, which provide a good opportunity to study the effects of diet and host species on gut microbiome. We collected fecal samples from yaks and Tibetan sheeps at different seasons when they were feed with different diets. Illumina data showed that major bacterial phyla of both animals are Bacteroidetes and Firmicutes, which agree with the previous reports. And the season effect had a higher impact on the gut microbiota than that of host species, though the animals are taxonomically distinguished each other at subfamily level. Since that the animal grazing differently at different seasons, this study indicated that diet can trump the host genetics even at higher taxonomic level. This finding provides a cautionary note for the researchers to link host genetics to the composition and function of the gut microbiota.Importance Yak and Tibetan sheep are very different from the size and genetics (from different sub-family). Nomadic Tibetan people keep them as main livestock and feeding them with same grazing systems, which provide a good opportunity to study the effects of diet and host species on the gut microbiota. Results indicated that diet can trump the host genetics even at higher taxonomic level. This finding provides a cautionary note for the researchers to link host genetics to the composition and function of the gut microbiota.