RT Journal Article
SR Electronic
T1 Genomic architecture and introgression shape a butterfly radiation
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 466292
DO 10.1101/466292
A1 Nathaniel B. Edelman
A1 Paul B. Frandsen
A1 Michael Miyagi
A1 Bernardo Clavijo
A1 John Davey
A1 Rebecca Dikow
A1 Gonzalo García-Accinelli
A1 Steven van Belleghem
A1 Nick Patterson
A1 Daniel E. Neafsey
A1 Richard Challis
A1 Sujai Kumar
A1 Gilson Moreira
A1 Camilo Salazar
A1 Mathieu Chouteau
A1 Brian Counterman
A1 Riccardo Papa
A1 Mark Blaxter
A1 Robert D. Reed
A1 Kanchon Dasmahapatra
A1 Marcus Kronforst
A1 Mathieu Joron
A1 Chris D. Jiggins
A1 W. Owen McMillan
A1 Federica Di Palma
A1 Andrew J. Blumberg
A1 John Wakeley
A1 David Jaffe
A1 James Mallet
YR 2018
UL http://biorxiv.org/content/early/2018/12/04/466292.abstract
AB We here pioneer a low-cost assembly strategy for 20 Heliconiini genomes to characterize the evolutionary history of the rapidly radiating genus Heliconius. A bifurcating tree provides a poor fit to the data, and we therefore explore a reticulate phylogeny for Heliconius. We probe the genomic architecture of gene flow, and develop a new method to distinguish incomplete lineage sorting from introgression. We find that most loci with non-canonical histories arose through introgression, and are strongly underrepresented in regions of low recombination and high gene density. This is expected if introgressed alleles are more likely to be purged in such regions due to tighter linkage with incompatibility loci. Finally, we identify a hitherto unrecognized inversion, and show it is a convergent structural rearrangement that captures a known color pattern switch locus within the genus. Our multi-genome assembly approach enables an improved understanding of adaptive radiation.