TY - JOUR T1 - Persistent bacterial coinfection of a COVID-19 patient caused by a genetically adapted <em>Pseudomonas aeruginosa</em> chronic colonizer JF - bioRxiv DO - 10.1101/2020.08.05.238998 SP - 2020.08.05.238998 AU - Jiuxin Qu AU - Zhao Cai AU - Yumei Liu AU - XiangKe Duan AU - Shuhong Han AU - Yuao Zhu AU - Zhaofang Jiang AU - Yingdan Zhang AU - Chao Zhuo AU - Yang Liu AU - Yingxia Liu AU - Lei Liu AU - Liang Yang Y1 - 2020/01/01 UR - http://biorxiv.org/content/early/2020/08/06/2020.08.05.238998.abstract N2 - This study characterized a genetically adapted Pseudomonas aeruginosa small colony variant isolated from a COVID-19 patient who suffered persistent bacterial coinfection and eventually recovered from critical illness. Specification and modification of the isolates discovered at genomic and transcriptomic levels with aligned phenotypic observations indicated that these isolates formed excessive biofilm with elevated quorum sensing systems.Competing Interest StatementThe authors have declared no competing interest. ER -