PT  - JOURNAL ARTICLE
AU  - Jiuxin Qu
AU  - Zhao Cai
AU  - Yumei Liu
AU  - XiangKe Duan
AU  - Shuhong Han
AU  - Yuao Zhu
AU  - Zhaofang Jiang
AU  - Yingdan Zhang
AU  - Chao Zhuo
AU  - Yang Liu
AU  - Yingxia Liu
AU  - Lei Liu
AU  - Liang Yang
TI  - Persistent bacterial coinfection of a COVID-19 patient caused by a genetically adapted <em>Pseudomonas aeruginosa</em> chronic colonizer
AID  - 10.1101/2020.08.05.238998
DP  - 2020 Jan 01
TA  - bioRxiv
PG  - 2020.08.05.238998
4099  - http://biorxiv.org/content/early/2020/08/06/2020.08.05.238998.short
4100  - http://biorxiv.org/content/early/2020/08/06/2020.08.05.238998.full
AB  - This study characterized a genetically adapted Pseudomonas aeruginosa small colony variant isolated from a COVID-19 patient who suffered persistent bacterial coinfection and eventually recovered from critical illness. Specification and modification of the isolates discovered at genomic and transcriptomic levels with aligned phenotypic observations indicated that these isolates formed excessive biofilm with elevated quorum sensing systems.Competing Interest StatementThe authors have declared no competing interest.