RT Journal Article
SR Electronic
T1 Immunoreactive peptide maps of SARS-CoV-2 and other human coronaviruses
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 2020.08.13.249953
DO 10.1101/2020.08.13.249953
A1 Mishra, Nischay
A1 Huang, Xi
A1 Joshi, Shreyas
A1 Guo, Cheng
A1 Ng, James
A1 Thakkar, Riddhi
A1 Wu, Yongjian
A1 Dong, Xin
A1 Li, Qianlin
A1 Pinapati, Richard
A1 Sullivan, Eric
A1 Caciula, Adrian
A1 Tokarz, Rafal
A1 Briese, Thomas
A1 Lu, Jiahai
A1 Lipkin, W. Ian
YR 2020
UL http://biorxiv.org/content/early/2020/08/14/2020.08.13.249953.abstract
AB Serodiagnosis of SARS-CoV-2 infection is impeded by immunological cross-reactivity to the human coronaviruses (HCoV) SARS-CoV-2, SARS-CoV-1, MERS-CoV, OC43, 229E, HKU1, and NL63. Here we report the identification of humoral immune responses to SARS-CoV-2 and other HCoV peptides that can be used to detect asymptomatic, mild and, severe SARS-CoV-2 infections, and may enable the discovery of biomarkers for immunity following infection or vaccination.Competing Interest StatementNM, SJ, CG, RaT, TB, and WIL are listed as the inventors on a patent filed that is related to findings in this study. Application: 63/005,865 Title: Peptide Sequences for Detection and Differentiation of Antibody Responses to SARS-CoV-2 and Other Human Corona Viruses Application Type PRO - Provisional Status: Filed Country: United States IRs: CU20309 IR Received: 2020-04-02 Filing Date: 2020-04-06 Inventor(s) : Nischay Mishra; W. Ian Lipkin M.D.; Rafal Tokarz; Shreyas Joshi; Cheng Guo; Thomas Briese;