TY - JOUR T1 - Experience-dependent increases in sharp-wave ripples near visual targets JF - bioRxiv DO - 10.1101/054171 SP - 054171 AU - Timothy K. Leonard AU - Kari L. Hoffman Y1 - 2016/01/01 UR - http://biorxiv.org/content/early/2016/05/18/054171.abstract N2 - We measured hippocampal sharp-wave ripples during goal-directed visual exploration in macaques. Exploratory sharp-wave ripples were more frequent on familiar trials, in the second half of search, and near the visual target (i.e., the goal location). These spatial and temporal properties may help SWRs coordinate hippocampal and extra-hippocampal firing sequences that guide actions based on past experiences. ER -