PT - JOURNAL ARTICLE AU - Lorenz Ulrich AU - Kerstin Wernike AU - Donata Hoffmann AU - Thomas C. Mettenleiter AU - Martin Beer TI - Experimental infection of cattle with SARS-CoV-2 AID - 10.1101/2020.08.25.254474 DP - 2020 Jan 01 TA - bioRxiv PG - 2020.08.25.254474 4099 - http://biorxiv.org/content/early/2020/08/25/2020.08.25.254474.short 4100 - http://biorxiv.org/content/early/2020/08/25/2020.08.25.254474.full AB - Six cattle (Bos taurus) were intranasally inoculated with SARS-CoV-2 and kept together with three naïve in-contact animals. Low-level virus replication and a specific sero-reactivity were observed in two inoculated animals, despite the presence of high antibody titers against a bovine betacoronavirus. The in-contact animals did not become infected.Competing Interest StatementThe authors have declared no competing interest.