PT  - JOURNAL ARTICLE
AU  - Vahid Jalili
AU  - Enis Afgan
AU  - James Taylor
AU  - Jeremy Goecks
TI  - Cloud Bursting Galaxy: Federated Identity and Access Management
AID  - 10.1101/506238
DP  - 2018 Jan 01
TA  - bioRxiv
PG  - 506238
4099  - http://biorxiv.org/content/early/2018/12/26/506238.short
4100  - http://biorxiv.org/content/early/2018/12/26/506238.full
AB  - Motivation Large biomedical datasets, such as those from genomics and imaging, are increasingly being stored on commercial and institutional cloud computing platforms. This is because cloud-scale computing resources, from robust backup to highspeed data transfer to scalable compute and storage, are needed to make these large datasets usable. However, one challenge for large-scale biomedical data on the cloud is providing secure access, especially when datasets are distributed across platforms. While there are open Web protocols for secure authentication and authorization, these protocols are not in wide use in bioinformatics and are difficult to use for even technologically sophisticated users.Results We have developed a generic and extensible approach for securely accessing biomedical datasets distributed across cloud computing platforms. Our approach combines OpenID Connect and OAuth2, best-practice Web protocols for authentication and authorization, together with Galaxy (https://galaxyproject.org), a web-based computational workbench used by thousands of scientists across the world. With our enhanced version of Galaxy, users can access and analyze data distributed across multiple cloud computing providers without any special knowledge of access/authorization protocols. Our approach does not require users to share permanent credentials (e.g., username, password, API key), instead relying on automatically-generated temporary tokens that refresh as needed. Our approach is generalizable to most identity providers and cloud computing platforms. To the best of our knowledge, Galaxy is the only computational workbench where users can access biomedical datasets across multiple cloud computing platforms using best-practice Web security approaches and thereby minimize risks of unauthorized data access and credential use.Availability and Implementation Freely available for academic and commercial use under the open-source Academic Free License (https://opensource.org/licenses/AFL-3.0) from the following Github repositories: https://github.com/galaxyproject/galaxy and https://github.com/galaxyproject/cloudauthzContact jalili{at}ohsu.edu, goecksj{at}ohsu.edu